The game includes the Deep Monkey Knowledge System. Players can build strategies that synergize with the abilities of individual Hero monkeys.
Each of them has activated abilities to eliminate tougher balloons. This game features Hero monkeys that can be boosted with 20 signature upgrades. Only a single monkey tower can reach tier 5 upgrade. Each monkey tower has 3 upgrade paths to combat a specific type of balloon. Some of the maps have 3D objects that serve as obstructions as they can block the line of sight for the monkey tower. On the other hand, they will face new Bloons like Purple Bloons, Fortified Bloons, and the B.A.D. This game includes the new Alchemist and Druid tower. The monkey towers and monkey groups can be upgraded for extra firepower. They have to assemble monkey towers, Heroes and abilities to clear waves of Bloons. Players can expect hours and hours of Bloons popping.
The skins for monkey towers can be upgraded that reflects their improved performance. Bloons TD 6 is an improvement of the prior Bloons TD game as it uses 3D graphics, new animations, and intense visual effects.